Molecular MRI of Intracranial Thrombus in a Rat Ischemic Stroke Model
نویسندگان
چکیده
منابع مشابه
Molecular MRI of thrombus in a rat ischemic stroke model
Introduction: Ischemic stroke is the leading cause of morbidity and the third most common cause of mortality in USA. The identification of the culprit thrombotic lesion, micro-emboli and the source of the embolus are all critical to patient management. EP2104R [1], a fibrin-specific molecular MR agent, was previously shown to enhance arterial and venous thrombi in large animal models (swine, ra...
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BACKGROUND AND PURPOSE Intracranial thrombus is a principal feature in most ischemic stroke, and thrombus location and size may correlate with outcome and response to thrombolytic therapy. EP-2104R is a fibrin-specific molecular MR agent that has previously been shown to enhance extracranial and venous sinus thrombi in animal models and, recently, in clinical trials. In this study, we examined ...
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ژورنال
عنوان ژورنال: Stroke
سال: 2010
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.109.575662